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[飲食養生] 研究發現中高強度體力活動可有效預防帕金森

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發表于 2018-9-23 07:10:06 | 只看該作者 回帖獎勵 |倒序瀏覽 |閱讀模式
 浙江大學醫學院王福俤教授、閔軍霞教授研究團隊的一項對2192例帕金森患者與54萬余健康人群對照的大數據分析研究發現,中高強度的體力活動可以顯著降低帕金森病發病風險。相關論文于21日在線發表于《美國醫學學會雜志》(JAMA)子刊《美國醫學會雜志網絡公開》(JAMA Network Open)。
  為深入探究體力活動是否可能預防帕金森病發生這一問題,研究團隊對2192例帕金森患者與54萬余健康人群開展了劑量反應分析。論文第一作者、浙江大學博士生方學賢表示,一個健康的成年人靜坐時保持舒適狀態的新陳代謝率為1梅脫(即MET,為人體新陳代謝單位),每周增加10梅脫小時體力活動,帕金森病發病風險可降低10%,每周增加10梅脫小時的高強度體力活動,也就是慢跑、騎行或游泳2小時至3小時,帕金森病發病風險可降低17%,而增加同樣時間的散步等輕度體力活動,并沒有顯著影響帕金森病的發病風險。
  研究團隊進一步開展了男性及女性的亞組分析,結果顯示體力活動對于帕金森病發病風險的保護作用在男性中更為顯著,而在女性中未能觀察到保護效應。
  王福俤表示,該成果能夠為帕金森病一級預防策略制定提供重要科學依據,推薦開展人群體力活動干預試驗,將為明確體力活動與帕金森病之間的關系提供更堅實的因果證據。

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